Wilmington was a city where Andy Taylor had to go in the season 5 episode, "Gomer Pyle U.S.M.C." Because it was "right by the base" to which Gomer Pyle was to report for Marine Corps service, Andy was able to drive Gomer there. It was unclear what business Andy actually had in the city, which in real life is quite remote to almost every other part of the state.

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