Opie has had many friends over the course of the episodes.
The Andy Griffith Show[]
A[]
- Arnold Winkler: (Opie and the Spoiled Kid) and (The Haunted House)
- Arnold Bailey: (Season 7 The Andy Griffith Show)
B[]
- Billy: (The New Housekeeper)
- Billy Gray: (One-Punch Opie)
- Billy Hollander: (Opie Steps Up in Class)
C[]
F[]
- Fred Simpson: (Opie's First Love) Opie's schoolmate.
H[]
J[]
- Jerry Parker
- Jerry: (The New Housekeeper)
- Jimmy
- Joey: (The Bookie Barber)
- Johnny Paul Jason
M[]
- Matt Merlis: (Barney Mends a Broken Heart) and (A Wife for Andy) Opie say's Matt Merlis is his best friend.
N[]
- Nat Pike: (Quiet Sam) - Four year old friend who told Opie a penny hit by lightning is worth 6 cents.
R[]
- Ralph Baker: (Bringing Up Opie)
- Ralphie: (The Manhunt)
S[]
- Steve: (Runaway Kid) He, Opie and Tommy push the Squad Car in front of the fire hydrant.
T[]
- The Wildcats: (The Keeper of the Flame) Opie's club members.
- Tommy: (The New Housekeeper) (The Manhunt)
- Tommy: (Runaway Kid) Plays cowboys with Opie and pushes the Squad Car in front of a fire hydrant.
- Trey Bowden